Follow a new generation of the Dutton family during the early twentieth century when pandemics, historic drought, the end of Prohibition and the Great Depression all plague the mountain west, and the Duttons who call it home.

Basketball star Mitch Wimmer discovers a passion for ballet while his best friend Bobby faces a life-changing accident and Mitch's estranged gay father returns, leading to new beginnings and reconciliations.

An older professor longing for motherhood must recalibrate her path to pregnancy when she realizes one of her favorite students is a potential sperm donor.