Life for former United Nations investigator Gerry Lane and his family seems content. Suddenly, the world is plagued by a mysterious infection turning whole human populations into rampaging mindless zombies. After barely escaping the chaos, Lane is persuaded to go on a mission to investigate this disease. What follows is a perilous trek around the world where Lane must brave horrific dangers and long odds to find answers before human civilization falls.

A girls' volleyball team and a boys' orchestra get caught out by the pandemic and are forced to self-isolate together in a country house in the middle of nowhere.

Liz and her daughter Amy move to Hamelin where a dark secret in Liz's past is uncovered by the restless spirit of the Pied Piper, who seeks out those who have gotten away with a crime, and punishes them by taking away their children.