Cavalcade of America is an anthology drama series that was sponsored by the DuPont Company, although it occasionally presented a musical, such as an adaptation of Show Boat, and condensed biographies of popular composers. It was initially broadcast on radio from 1935 to 1953, and later on television from 1952 to 1957. Originally on CBS, the series pioneered the use of anthology drama for company audio advertising. Cavalcade of America documented historical events using stories of individual courage, initiative and achievement, often with feel-good dramatizations of the human spirit's triumph against all odds. This was consistent with DuPont's overall conservative philosophy and legacy as an American company dating back to 1802. The company's motto, "Maker of better things for better living through chemistry," was read at the beginning of each program, and the dramas emphasized humanitarian progress, particularly improvements in the lives of women, often through technological innovation.

After the death of a United States Senator, the idealistic Jefferson Smith is appointed as his replacement in Washington. The naive and earnest new senator soon finds himself battling political corruption.

Longfellow Deeds lives in a small town, leading a small town kind of life. When a relative dies and leaves Deeds a fortune, Longfellow moves to the big city where he becomes an instant target for everyone. Deeds outwits them all until Babe Bennett comes along. When small-town boy meets big-city girl anything can, and does, happen.

A fledgling producer finds himself at odds with his workers, financiers and his greedy ex-wife when he tries to produce live musicals for movie-going audiences.

Virginia Cunningham is confused upon finding herself in a mental hospital, with no memory of her arrival at the institution. Tormented by delusions and unable to even recognize her husband, Robert, she is treated by Dr. Mark Kik, who is determined to get to the root of her mental illness. As her treatment progresses, flashbacks depict events in Virginia's life that may have contributed to her instability.

Out-takes (mostly from Warner Bros.), promotional shorts, movie premieres, public service pleas, wardrobe tests, documentary material, and archival footage make up this star-studded voyeuristic look at the Golden age of Hollywood during the 30s, 40, and 50.

Nan Reynolds encourages her copywriter husband Bill to open his own agency. Nearly out of business, he finally gets a client. Former girlfriend Patricia Berkeley writes a very successful commercial for the client and neats up their old romance. Wife and girlfriend struggle over Bill.

Father O'Malley is sent to St. Mary's, a run-down parochial school on the verge of condemnation. He and Sister Benedict work together in an attempt to save the school, though their differing methods often lead to good-natured disagreements.

A police detective's violent nature keeps him from being a good cop.

Extra-marital fun and games at a convention of the Honeywell Rubber Company in Atlantic City. President J.B. Honeywell is to choose a new company sales manager. T.R. Kent and George Ellerbe are two salesmen who both want the job. However, they both get into trouble: T.R. is discredited when jealous saleswoman, Arlene Dale, interferes with his attempted seduction of Honeywell's daughter, Claire, and George attempts to seduce Nancy Lorraine. The position of sales manager is bestowed upon a drunken employee as a bribe after he catches J.B. about to visit "Daisy La Rue, Exterminator." Considered a lost film.

A gentleman thief charms a Viennese baron's wife and also conducts a daring daylight robbery of a jeweller's shop.

A Marshal must face unpleasant facts about his past when he attempts to run a criminal gang out of town.

Pa Higgins has decided to retire but winds up being forced to run for mayor. Ladd is both boyfriend to the Higgins girl and the son of Pa's opponent.

In 1899 Alaska, miners have to protect themselves from a phony legal team trying to steal their gold claims.

On her way by stagecoach to visit relatives out west, Flower Belle Lee is held up by a masked bandit who also takes the coach's shipment of gold. When he abducts Flower Belle and they arrive in town, Flower Belle is suspected of being in collusion with the bandit.

Harry and Inez are a dance team at the Wonder Bar. Inez loves Harry, but he is in love with Liane, the wife of a wealthy business man. Al Wonder and the conductor/singer Tommy are in love with Inez. When Inez finds out that Harry wants to leave Paris and is going to the USA with Liane, she kills him.

After a group of convicts escapes from prison, they take refuge in the wilderness. While most of the crew are ruthless sociopaths, Jim Canfield is an innocent man who was jailed under false pretenses. When Canfield and his fellow fugitives reach an isolated farming settlement where the men are all away, it creates tension with the local women. Things get direr when rumors of hidden money arise, and Canfield discovers that the man who framed him is part of the community.

Society heiress Joan Bradford rebels against her mother's choice of a future husband by masquerading as a working class girl and dating a window washer.

A woman falls for a younger man with severe mental problems.

A toothpaste magnate's mischievous daughter, tired of her father's traditional ways of conducting business, joins forces with her father's rival and a crazy inventor. Together they create "Cocktail Toothpaste". The new concoction tastes like whiskey in the morning, a martini at suppertime, and champagne at night.