Four young filmmakers try to raise money for their project by telling potential investors that Robert De Niro is on board -- now, they have to find him.

Upon discovering a coded message in the self help book "6 Dynamic Laws for Success (In Life, Love & Money)" which purportedly reveals the location of $2.4 million missing from a bank robbery gone bad, a demoralized ex-used car salesman sets out on a quest to find the money and remake himself in the process. However, he soon discovers he’s not the only one after the cash, and that the road to riches and self-improvement is littered with irate ex-wives, litigious fiancés, household calamities, accidental murders, and love at first sight.

An aging neuroscientist teams up with a group of young graduate students to prove his hypothesis that individuals with disabilities hold the key to unlocking a sixth sense before his past catches up with him.