Five years after a war versus the unknown, humans are used as weapons against one another.

Dealing with an illness and troubled past, an isolated man applies for the Mars Survival Mission with hopes to colonize Mars after the Earth has become over populated. Everett Curtis never fit in on Earth, and so when the chance for him to apply to become one of the first settlers on Mars arises he jumps at the chance. Befriending a local journalist and an old friends sister, he learns that Earth may be just as new to him as Mars.

721 days into the zombie apocalypse, 3 survivors take refuge for the night in an old abandoned farmhouse. While the house seems safe and secure, the trio soon discovers that zombies are the least of their problems.