Anne Shirley, a redheaded eleven-year-old girl, moves from an orphanage to Green Gables, home of the elderly Cuthbert siblings Mathew and Marilla. Her abundant imagination, cheer, and earnest heart begin to change the people around her.

In the year 2024, the world has collapsed. Grotesque monsters lurk amongst the ruins of Japan, while remaining people scrape together what they can to survive. Kiruko, an odd-job girl in Nakano, accepts a mysterious woman's dying wish to take a boy named Maru to a place called Heaven. Maru is convinced that there will be a boy there who looks exactly like him.

A typical morning. The usual music. Their normal lives. The peace these seven girls experience will suddenly be destroyed. By the living dead... zombies. A reality that they never wanted a part of, an amazing and terrifying zombie world. They all share one wish: "We want to live." These girls will struggle through this saga, in order to achieve a miracle.

The curtain rises on Sarasa Watanabe, a starry-eyed 5'10" student who hopes to perform as a male lead role in the all-female Kouka Acting Troupe. She forms a friendship with her new roommate, a former idol. Together, they’re in for the role of a lifetime.

Anne Shirley goes through many adventures before she ends up in Green Gables. After losing her parents, little Anne is taken in by the Thomas family, with whom she moves in and helps look after the children and do the housework. In the meantime, she discovers more about herself, including that her name is “Anne”, not “Ann”. She is simply adorable and her creativity brings joy to difficult days.

The anime re-imagining of the original live-action series follows the Winchester brothers Sam and Dean as they hunt creatures and other supernatural phenomena in the American countryside. The storyline covers the first two seasons of the live-action version, as well as original episodes.