Chicagoan Frank Gallagher is the proud single dad of six smart, industrious, independent kids, who without him would be... perhaps better off. When Frank's not at the bar spending what little money they have, he's passed out on the floor. But the kids have found ways to grow up in spite of him. They may not be like any family you know, but they make no apologies for being exactly who they are.

When a young boy vanishes, a small town uncovers a mystery involving secret experiments, terrifying supernatural forces, and one strange little girl.

Dr. Temperance Brennan and her colleagues at the Jeffersonian's Medico-Legal Lab assist Special Agent Seeley Booth with murder investigations when the remains are so badly decomposed, burned or destroyed that the standard identification methods are useless.

The Pritchett-Dunphy-Tucker clan is a wonderfully large and blended family. They give us an honest and often hilarious look into the sometimes warm, sometimes twisted, embrace of the modern family.

After many years spent at the “Cheers” bar, Frasier moves back home to Seattle to work as a radio psychiatrist after his policeman father gets shot in the hip on duty.

Adrian Monk was once a rising star with the San Francisco Police Department, legendary for using unconventional means to solve the department's most baffling cases. But after the tragic (and still unsolved) murder of his wife Trudy, he developed an extreme case of obsessive-compulsive disorder. Now working as a private consultant, Monk continues to investigate cases in the most unconventional ways.

On her sixteenth birthday, Sabrina Spellman discovers she has magical powers. She lives with her 600-year-old aunts Hilda and Zelda as well as talking cat Salem in the fictional town of Westbridge, Massachusetts.

The off-kilter, unscripted comic vision of Larry David, who plays himself in a parallel universe in which he can't seem to do anything right, and, by his standards, neither can anyone else.

ER explores the inner workings of an urban teaching hospital and the critical issues faced by the dedicated physicians and staff of its overburdened emergency room.

The story of an inner-city Los Angeles police precinct where some of the cops aren't above breaking the rules or working against their associates to both keep the streets safe and their self-interests intact.

A provocative legal drama focused on young associates at a bare-bones Boston firm and their scrappy boss, Bobby Donnell. The show's forte is its storylines about “people who walk a moral tightrope.”

The high commander of an alien expedition lands on Earth -- what he considers to be the least-important planet -- in human form as Dick Solomon. Along for the ride are his alien compatriots Harry, Sally and Tommy -- who is the eldest of the group but is now angrily trapped in a teen's body.

Best friends Raven and Chelsea, now both divorced mothers, are raising their children in a house together. Their house is turned upside down when they realize one of Raven's children inherited the same psychic abilities as their mother.

Obstetrician/gynecologist Mindy Lahiri tries to balance her personal and professional life, surrounded by quirky co-workers in a small medical practice in New York City.

Follow four college roommates as they arrive at New England's prestigious Essex College. A bundle of contradictions and hormones, these girls are equal parts lovable and infuriating as they live out their new, free lives on campus.

The coming of age events and everyday life-lessons of Cory Matthews, a Philadelphian who grows up from a young boy to a married man.

The story of Bill Henrickson and his life in suburban Salt Lake City, balancing the needs of his three wives -- Barb, Nicki and Margene-- their seven kids, three new houses and the opening of his newest hardware store. When disturbing news arrives about Bill's father, he is forced to reconnect with his polygamist parents who live on a fundamentalist compound in rural Utah.

The exploits of identical twins Liv, a former television star back home in Wisconsin and in the process of adding movie star to her credits, as well as beginning to focus on her music career, and Maddie, an outstanding student and basketball phenomenon recovering from an injured knee. The series centers on the unbreakable bond the twins share though they have wildly different personalities. To complicate their teenage lives, both parents work at their high school and their younger brothers are always stirring up trouble.

Leo is an ordinary teenager who has moved into a high-tech "smart'' house with his mother, inventor stepfather and Eddy, the computer that runs the house. Leo's life becomes less ordinary when, one day, he discovers a secret underground lab that houses three experiments: superhuman teenagers. The trio -- Adam, the strong one, Bree, the fast one and Chase, the smart one -- convinces Leo and his parents to let them leave their lab and join Leo at school, where they try to fit in while having to manage their unpredictable bionic strengths. As Leo figures out a way to keep his new pals' bionic abilities a secret, they help him build self-confidence.

Four teenage friends move from Minneapolis to Los Angeles to form a potential chart-topping boy band after Kendall is inadvertently discovered by an eccentric record executive, Gustavo Rocque. As they seize this opportunity of a lifetime, these friends embark on an exciting comedy and music-filled journey to prove to themselves and their record label that they are serious about their new career choice.