In the small, fictional Yorkshire town of Skelthwaite is an engaging story of life, love, family and people’s ever-changing fortunes in rural England. Set against the rugged landscape of Yorkshire, it follows the busy professional and family lives of District Nurses, as they bring nursing and emotional care to young and old alike. The first four series concentrates on the lives of district health nurses Peggy Snow and Ruth Goddard. The story expands to focus on the lives of more Skelthwhaite residents, particularly those related to the nurses as well as those employed in a local toilet tissue factory.

Follows the staff and patients of a Yorkshire cottage hospital in the 60s, embroiled in tangled love lives and bitter power struggles.