A group of heroic firefighters at Seattle Fire Station 19—from captain to newest recruit—risk their lives and hearts both in the line of duty and off the clock. These brave men and women are like family, literally and figuratively, and together they put their own lives in jeopardy as first responders to save the lives of others.

Lee Callahan begins to suspect her next-door neighbor is a serial killer.

Charlie and Gerald reunite their failed 2000's boy band for a competition whose prize money could remedy all of their financial woes. What could go wrong?

Amidst a super virus that ravages most of the world’s population, a tenacious microbiology student leads a small team through a rogue planned exposure. But the human trials end tragically, taking his friends’ lives one by one and leaving potential treatments untested. As he becomes more and more isolated, the line between what’s real and what’s not begins to blur.

Nora has come home to settle her father's accounts after his suicide.