Contestants race across the country in search of relatives they have never met, in hopes they will reach the finish line first and win the grand prize. Four teams (red, blue, green, black) are given clues and challenges along the way that lead them to people who share the same DNA. The last-place finisher at each stage of the competition receives a strike. Three strikes and that team is out.

Anna, a young slave girl, is rescued and adopted by Christians in 2ND Century Smyrna, and befriended by their aged bishop, Polycarp. As Anna is taught by Polycarp and her new family, she struggles to reconcile her beliefs with those of the Christians. When the Roman proconsul demands that all citizens worship Caesar to show their allegiance to Rome, Polycarp and the Christians must find courage to stand for their faith against the growing threat of persecution. Anna is forced to come to grips with the truth and choose whom she is willing to live, and die for.