Dr. Daniel Pierce, a neuroscientist and professor, is recruited to help the federal government crack difficult cases. His intimate knowledge of human behavior and masterful understanding of the mind give him an extraordinary ability to read people, but his eccentric view of the world and less-than-stellar social skills can often interfere with his work.

Patrick, the man with everything, risks losing it all after a drunken boy's night out before his wedding day. Faced with the aftermath, it is up to him to remove all obstacles to achieve his ultimate goal: acceptance.