Atikah, a young doctor who is sweet, sincere, cheerful, and super busy, lives happily with Mutiara, her only sister who suffers from lupus.

Five teenage best friends from town: the daredevil Natasha, the foppish Diana, the dupable Davina, Kathy the poet girl, and the cuckoo sissy boy Rhonda decide to spend their holiday in a secluded villa in Puncak Mountain.

Mella is haunted by memories of her sister who is suspected of being autistic. The younger brother died in a car accident. Mella became close to the autistic teenagers.

The passion and dream of Barack Obama, the president of the United States, inspired Hendra. He instilled the power of that dream in his granddaughter, Margareth, who he sent to Assisi Elementary School, where the president used to go to school.