Surgeon Crisp announces to his student doctors and friends that he has solved the problem of limb-grafting, and shows proofs. Among those deeply interested is Mortmain, a musician and a friend of the surgeon.

Betty is away at college when her parents, Mr. & Mrs. Bunny, come to visit. Mr. Bunny goes for a stroll while Mrs. Bunny looks at Betty’s furnished room, which she finds unsatisfactory. Mr. Bunny meets boarding house owner Mrs. Sweet and goes to her home for a bit of harmless flirtation. Meanwhile Mrs. Bunny insists Betty move and by happenstance they head to Mrs. Sweet’s. Mr. Bunny tries to hide from them and many comic situations ensue.

Willfull, headstrong and inclined to be sporty, but withal, a very lovable girl, Thomasin Webb (called Tommy for short) keeps her Aunt Sarah, with whom she lives, on the jump. Guy Dunbar becomes deeply interested in Tommy, first from a psychological point of view, then fascinated by her personality. George Hilton, a society rounder, is after Tommy's money

Two vaudeville performers, Steve Jenks and Stella Triplight, receive urgent bookings in different towns but find themselves with each other's trunks due to a mix-up by a baggage agent. To perform, they improvise by wearing the wrong clothes – Steve in Stella's dresses and Stella in Steve's suits – and unexpectedly become huge hits, leading them to team up, share their wardrobe, and find romance after discovering their shared success and loneliness.

When Rupert's uncle tells him he must quit his writing and offers him a real job in his tannery, the young man rises in his wrath and dramatically leaves his uncle's home, saying that he will go forth to the big city and carve out his fortune with his pen. After many hardships and cold rebuffs from the cruel publishers and editors he begins to despair