When a cheer squad practices their routines on Halloween weekend in an abandoned school, they are picked off one by one by an unknown killer.

Several years after the murderous events of the first movie left her father dead, Emma is now living with her aunt Angela and navigating high school. Angela’s husband begins to suspect that Emma may not be as innocent as she appears and suggests sending her off to boarding school. Meanwhile, a new girl at school seems to know Emma’s secrets, leaving Emma no choice but to slip back to her old ways and take care of her enemies by any means necessary.

After the murder of her childhood best friend and fellow classmate, Kathleen must catch a killer who's preying on young girls around campus.