Eastern Ukraine, May 2014. Part of the historic Donbas region falls to pro-Russian separatists. Young journalist Stanislav Aseyev reports for several Ukrainian media outlets from Donetsk, his hometown. In May 2017, he is kidnapped and spends 962 days in detention, mainly in a former cultural center, converted into a prison, called Izolyatsia —or Isolation.

The film centers on Ukrainian surgeon Serhiy, who is captured by the Russian military forces in the conflict zone in Eastern Ukraine, and while in captivity, he is exposed to horrifying scenes of humiliation, violence and indifference toward human life. After his release, he returns to his comfortable middle-class apartment and tries to find a purpose in life by rebuilding his relationship with his daughter and ex-wife. He learns how to be a human being again, how to be a father and help his daughter, who needs his love and support.