A drama about a multi-generational family of cops dedicated to New York City law enforcement. Frank Reagan is the New York Police Commissioner and heads both the police force and the Reagan brood. He runs his department as diplomatically as he runs his family, even when dealing with the politics that plagued his unapologetically bold father, Henry, during his stint as Chief.

A former professional dancer, Brooke, and her brother Cary, an aspiring actor, try to find their place in the world while wrestling with their feelings about their 13-year-old brother Chase's sudden rise to internet fame.

Life is really tough for Julie Kessler and Billy Epstein, two thirty-something aspiring comics living and working in New York City. While their friends and acquaintances move on to find success and love, they continue to struggle with careers and relationships, getting more bitter by the day.

When Billie learns that her estranged parents' lives are at risk, she tries to help them by robbing a bank. In her botched robbery attempt, she takes a hostage named Franny, who turns out to be a charmingly impulsive pregnant teenager with nothing left to lose. Together, Billie and Franny embark on a chase through scenic American landscapes, clashing and struggling for common ground in hopes for a brighter future.

Unceremoniously dumped by his college girlfriend Margaret during a trip to Cambodia, lovelorn American Keith returns to Philadelphia and teams with his best friend Chainsaw to form a "relationship investigation" team devoted to revealing unfaithful husbands, wives, boyfriends, and girlfriends for the two-timing louses that they truly are.