Each tenant of an old building called "Salsipuedes" has a story to tell. Crazy adventures, gossip, scandals, and both beloved and unfriendly neighbors are part of this entertaining series.

Cristóbal is a handsome, ambitious and challenging surgeon who never follows the rules, and is just the exact opposite of his partner and friend Santiago, who is a rigid man caught in a routine marriage. For her part, Julia is a woman who after the birth of her son, abandoned her dreams of becoming a doctor, and without realizing it ended up saddened, living under the shadow of Santiago and his professional achievements.

Teresa is an artificial intelligence device that comes from the United States to Colombia to be tested in a real world and with a very particular family: Los Rico. Teresa arrives just at Christmas time, where between novenas, fritters and custard, she will discover deep connections with her new family.