Set against the backdrop of an unexpected wedding invitation, a chance reunion after two years of estrangement forces two women to confront their deeply entangled, hidden past. As their unresolved history resurfaces in the shadows of the Chatterjee household, an unsuspecting husband finds himself increasingly caught in a web of unspoken anxieties.

After Suman suffers an accident, the two women in his life - Meghna, the wife, and Shubhra, the ex-wife - are compelled to meet each other. Ardhangini revolves around the awkward emotional duel between the two wives - past and present - in a time of personal crisis.