London, 1605. Robert Catesby, a 33-year old Warwickshire gentleman, devises a plot to blow up Parliament and kill the King.

As a young woman lies dying in hospital, we journey through her subconscious as she faces one last fight to say goodbye to her loved ones.

Susannah is living a typically quiet and dusty life in the suburbs with her husband Paul, when an unexpected visit from her son, Piers, surfaces a dark secret that has been brewing since he left the nest 15 years ago. As Susannah struggles to come to terms with Piers' relationship with his new girlfriend, her typical mediocre existence is slowly stripped away to reveal an obsession that is anything but typical or secret.

Orthodox tells the story of Benjamin, an Orthodox Jewish man who alienated himself from his community by becoming a boxer. When his life took a wrong turn he ended up in prison, losing his wife and children in the process. Now he is out and desperate to reintegrate, he finds that acceptance harder than he ever imagined. He turns back to his old boxing coach thinking there he has an ally, but a truth about the past emerges which leaves him even more isolated than he once thought. Benjamin must make a choice which will effect not just his own future but the life of a young Jewish boy whose life he can relate to. He is determined not to allow history to repeat itself.