Oppie is a smart hardworking orphan from a low-class family. She lives with her older brother, Rangga, in a house that also serves as a shelter for orphans and abandoned children. Meanwhile, Laura is a spoiled arrogant girl, who only finds fun as her life purpose thanks to the luxurious living provided by her conglomerate. Both of them attend Bentara Budaya High School, one of the famous high schools in Jakarta, where Laura is popular as a rich girl who likes parties, while Oppie is popular because of her intelligence & scholarship. They didn't like each other yet they always crossed path.

Nayla, a 15-year-old girl who lives in a simple family, is cheerful, diligent, smart, good at basketball, and diligent in worship. One day, unusual things began to happen to Nayla. She started falling frequently and walking strangely. When her mother took her to see a doctor, Nayla was diagnosed with Spinocerebellar Ataxia, a rare disease.

Evita is a beautiful successful presenter. Her shows always touch the hearts of viewers, in which helping families to find their missing family members. The reason being, is because she still determined to find her long lost little sister, Mira. Her adoptive mother, Hera, always blamed her for the disappearance of Mira, her biological child.

Vania Vanila, a beautiful and famous artist who falls in love with her new apartment neighbor, Morgan. Actually, Morgan comes from another planet. Four hundred years ago, she fell to Earth, precisely in Batavia. Since then, she has lived on Earth and cannot return to her planet.