In a small town in northern Mexico, where two drug cartels rule, the young man Lupe embraces his dangerous fate. He transforms into Coyotl, a mythical creature that is half man and half beast. With this transformation, Lupe wants to become the protector his people so desperately need.

A tormented father witnesses his young son die when caught in a gang's crossfire on Christmas Eve. While recovering from a wound that costs him his voice, he makes vengeance his life's mission and embarks on a punishing training regimen in order to avenge his son's death.