Dr. Bashir Hamed, a Syrian doctor with battle-tested skills in emergency medicine, makes the difficult decision to flee his country and build a new life in Canada with his younger sister Amira. Bash works to navigate a new environment after earning a coveted residency in the Emergency Department of one of the best hospitals in Toronto, York Memorial.

Across various timelines and locations, the fates of four characters intertwine as they struggle to find connections and meaning in a world transformed by climate change.