After escaping prison during a monster attack, convict Wu Chuan must navigate a city overrun by prehistoric creatures and lead a desperate fight to save his trapped mother and stop an ancient beast from destroying the city.

In the late years of the Sui Dynasty, chaos reigned across the land. On the tenth day of the third month of the fourteenth year of Daye, a mutiny broke out in Jiangdu, Emperor Yang was killed, and the divine beast Kui Ox was left ownerless. Rebel forces from all directions and local powers mobilized to Jiangdu in search of the legendary divine sword that could subdue the Kui Ox. A scholar journeyed to Jiangdu for the imperial examination and, by twist of fate, arrived at the mysterious Caohang Ferry Inn. Within the small inn, there were aspiring scholars like him who possessed ambitions but were scattered across the world, as well as a delicate and enigmatic mute woman, and seemingly unreliable free-spirited martial artists.

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The last bloodline of the declining dragon family Feng Yi Fan, accidentally swallowed the ancestral secret treasure Dragon Nine pills and magically gave birth to the talented Long Jiuzi. Jiuzi is able to speak the moment he was born, and the legend has it that Jiuzi's flesh and blood are able to refine and come together itself, and will give eternal life. This caused Jiuzi to be coveted by many evil forces, so the family embarked on an escape journey. The crazy journey to escape with near-death experiences allowed the family to grow as a whole, and also allowed the talented Jiuzi understand the responsibility and role of everyone's existence. In the end, he was able to protect everyone with teamwork and cooperation.