30-year-old single Mary Richards moves to Minneapolis to start a new life after a romantic break-up. There she reacquaints with Phyllis who rents her a room, and meets her upstairs neighbor and new best friend Rhoda. Mary unexpectedly lands a job as associate producer at the TV station WJM, where she works alongside her bristly boss, Lou; the comical newswriter, Murray; and the newscast's often-incompetent anchor, Ted.

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As their romance unfolds, Jade and David's growing love for one another becomes the scorn of Jade's father. However, when Jade's grades begin to drop, her father forbids the young couple from seeing each other for 30 days. Driven insane with frustration and desire, David attempts to reverse the decision, with catastrophic results.

The story of three wildly neurotic characters: a facially disfigured girl, a homosexual paraplegic, and an introvert epileptic who, after leaving the hospital, set up housekeeping together in a cottage where they support each other.

A jeweller is killed in a gang robbery leaving the daughter as the only witness. When the police can't build a case against him she decides to go undercover to infiltrate the home of the killer's brother. Slowly she is drawn into the world of the rival gangs.