Raden Kian Santang, who was assigned by Uncle Guru, was looking for the lost book of Buana Kosa and at the same time saving his brother, Surawisesa. Unfortunately, their journey is hampered in a village full of mystery and supernatural terror.

In 1920s Dutch East Indies, Giandra, a young doctor from STOVIA, reads about Layla—a girl shackled in a remote village as a "cure" for mental illness. Disturbed, he travels to Karuhun, where tradition and mysticism prevail over science. Guided by journalist Rikke, who warns him with three words—Culture. Mysticism. Superstition.—Giandra must confront a clash between modern medicine and ancestral belief.