In cases ripped from the headlines, police investigate serious and often deadly crimes, weighing the evidence and questioning the suspects until someone is taken into custody. The district attorney's office then builds a case to convict the perpetrator by proving the person guilty beyond a reasonable doubt. Working together, these expert teams navigate all sides of the complex criminal justice system to make New York a safer place.

A police officer patrols a Philadelphia neighborhood hard-hit by the opioid crisis. When a series of murders begins in the neighborhood, Mickey realizes that her personal history might be related to the case.

New York City police detective Anthony is torn between following the rules and being a good son. Caretaker of his debilitated mother Joyce, Tony wants the American dream but finds himself in a nightmare.