The story follows the Castaño Gil family, a prosperous cattle ranching family marked by the kidnapping and murder of patriarch José Castaño by the guerrilla. This event triggers the decision of brothers Fidel, Vicente, and Carlos to form a self-defense army to fight the guerrillas, intensifying the armed conflict in Colombia. However, what seemed like a unified struggle is threatened by betrayal.

The series tells of cases based on real events, which show how a woman is able to be at peace and end her suffering in the most lethal way, killing. In each episode, the protagonist tries to find a way to get rid of her problems, motivated by love, revenge, pain, desperation, resentment, contempt, hatred, beatings, addiction or frustration.