U.S. Marshal Mary Shannon must hunt down witnesses for federal cases in the witness protection program while also managing a rather dysfunctional family and her own personal life.

After Faye and her psychotic boyfriend, Vince, successfully rob a mob courier, Faye decides to abscond with the loot. She heads to Reno, where she hires feckless private investigator Jack Andrews to help fake her death. He pulls the scheme off and sets up Faye with a new identity, only to have her skip out on him without paying. Jack follows her to Vegas and learns he's not the only one after her. Vince has discovered that she's still alive.

Three young men decide to make easy money by mass kidnapping. After careful preparations, they hijack the school bus and take 26 children and the driver as hostages. However, the bravery and the wit of the old driver could spoil their plan for the perfect crime.

A Central American revolutionary is captured and tortured by government forces. He escapes and flees to the US, hiding out in a rural area where he is sheltered by a Christian sanctuary movement. His wife gets a job at a local diner run by one of the town's shadier women, and soon a CIA assassination team shows up, looking for him.