Retired farmer and widower Alvin Straight learns one day that his estranged brother Lyle has suffered a severe stroke. Alvin is determined to make things right with Lyle while he still can, but his brother lives in Wisconsin, while Alvin is stuck in Iowa with no car and no driver's license. He then has the idea of making the trip on his old lawnmower, thus beginning a picturesque and at times deeply spiritual odyssey.

The story of Mary Thomas, the mother of basketball star Isiah Thomas, and how she fought to keep her family together and her sons out of trouble despite the surroundings of poverty, drugs, crime and violence of their ghetto neighborhood.