On October 13, 1972, Uruguayan Air Force Flight 571, chartered to take a rugby team to Chile, crashes into a glacier in the heart of the Andes.

At the age of 13, Rafael Bregman has already lost his virginity, but has never kissed a girl. With his pimple-riddled face, his dysfunctional family, and a lowered self-esteem, getting this much anticipated first kiss proves trickier than expected. It's now time for Rafa to build up some self confidence and attract the attention of his class mate, Nicole...

Tito is 13 years old and extremely gifted at soccer, his genius brings him a contract that lifts him and his family out of poverty. He shines with his goals, but turns into a petty player, drops out of school, and has no friends. Tito becomes the breadwinner of the family and his father no longer has the authority to force him to finish school. When Tito is one step away from consecrating himself, something unexpected will make his dream disappear. Having lost everything he must return to his village. Tito will have to face the most difficult challenge of his life: to stand up and keep going.

Olga, Teresa and Pilar have been friends since they were born. For years they vacationed together with their parents, and later together on their own. A few years ago, Teresa got married, and for some years they didn't see each other as much. Teresa's divorce prompts a reunion, so the three of them rent a small house for the weekend. In their first day together, it becomes obvious that everything they share is in their past. They have grown apart.

Lila, a dedicated cleaning staff employee, runs an unofficial cafeteria with her friend Marcela. When she is officially promoted to direct it, tensions arise with Marcela that upset the delicate balance of the office after 30 years of camaraderie.

Based on the play of the same name, the film features Siamese twins Annie and Dani, who face physical separation in an act that is as surgical as it is existential. Willie, another brother who has to operate on them, confesses his desire to be a Siamese and asks to sew himself to one of them. The tensions and obsessions of the cast become entangled with the fantastic fiction; meanwhile, the main location threatens to collapse.

In Montevideo, Sonja cares for her invalid mother, works in a garment factory, and has little going for her. Her neighbor Modesto, an older man who lives alone, types anonymous letters to her. Her mother is difficult -- demanding and miserable, afraid of death. Sonja meets Ernesto, a nurseryman, and finally there may be some possibilities in her life. Does freedom beckon?

When his long-lost brother resurfaces, Jacobo, desperate to prove his life has added up to something, looks to scrounge up a wife. He turns to Marta, an employee at his sock factory, with whom he has a prickly relationship.

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A divorced taxi driver shows up with a black eye at the home of his ex-wife’s new family; he’s been invited to dinner and he desperately wants to reconnect with his young daughter. A professional magician’s car breaks down and he ends up spending an emotionally intense night with a young, widowed toll booth worker. A singer songwriter serving a lengthy prison sentence is released for one night to perform at a local community centre. These three deeply engaging stories about yearning for connection unfold in parallel, one New Year’s Eve in a small town in central Uruguay, balancing the universality of human suffering with a powerful sense of hope.

Claudio is promoted to policy coordinator in his insurance company, but he has to move to a remote small town for the position, and after arriving numerous cars begin to be set on fire. Claudio is pressured to cover the cars' insurance in a hostile environment, and as he tries to do so he will discover that many things are not what they appear to be.

Miguel Ángel García Mazziotti, a Río de la Plata's decadent showbiz gay figure, receives the visit of his daughter Virginia, of whom he has been distanced for years. "The Fat", as everybody calls him in Punta del Este, openly rejects her visit, but when realizes will become a grandfather he can't help getting thrilled and celebrate Virginia's happiness. As a result they share a real familiar weekend that, as many families, to be happy it has to be fake.

Nalu lives with Ruben, her father, in a small country town near the Brazilian border with Uruguay. When Ruben realizes that his daughter is becoming a woman, an ambiguous closeness begins to develop between them.