Tragedy, betrayal and a mysterious discovery fuel a woman's vengeance for the loss of her tribe and family.

In the dead of night, a body donated for organ transplants mysteriously disintegrates into ashes. Soon after, five recipients, given a heart, corneas, lungs, liver, and kidneys, begin to develop supernatural powers. A teenage girl gains immense strength, a hipster manipulates electromagnetic waves, a novelist summons powerful gusts, a factory manager can heal others, and a woman discovers a strange, still-unidentified ability. Together, they form a reluctant but heroic team known as "HI-FIVE." But they aren't the only ones transformed. A cult leader who received the donor’s pancreas gains the terrifying power to drain life energy and sets his sights on stealing the abilities of HI-FIVE to achieve godlike domination.

Choi Jihoon is assigned to Daehun High School, the worst high school in Korea. He pledges to be the ‘Jjang (Top gangster)’ here, but the reality is quite tough.