A pair of young student doctors get involved in a secret society of surgery fetishists and monster makers called the "Cutters Club", overseen by the maddest of doctors. Creatures, carnage, mayhem and macabre malpractice combine in this maniacal movie, brought back from the brink of oblivion to take its rightful place as Todd's fevered cinematic swan song.

A fallen foot tall Homunculus called Marvin (a part human/part reptile creature) is imprisoned in a birdcage by a vengeful lover who is bidding to become the world's most powerful vampire.