After Jay Leno's second retirement from the program, Jimmy Fallon stepped in as his permanent replacement. After 42 years in Los Angeles the program was brought back to New York.

A former country star, Misty Jones, comes out of seclusion to investigate the disappearance of her missing niece, a rising country musician and must grapple with her own past and Nashville’s seedy underbelly. Her search uncovers a murky side of Nashville where no one, including Misty, is who they seem.