The marriage is over, now what? For Laura, Ana Lia, Joana, and Claudinha, the answer is: friendship! Together, they face the challenges and joys of single life after 40.

Mia is a self-centered witch who possesses an unusual power: whoever kisses her falls in love with her or falls back in love with the last person they loved. In one of her jobs, however, she ends up falling in love with the woman she was supposed to cast a spell on.

Cleo, a 43-year-old astronomer who is pregnant and emotionally fragile, is surprised by a visit from Nalu, her half-sister of Indigenous descent. The encounter reveals dark secrets and stirs up fragmented memories in Cleo, leading the two of them down a path of mysterious investigations.