Comic Russell Brand uses drugs, sex and fame in a quest for happiness, only to find it remains elusive. As he explores iconic figures such as Gandhi, Malcolm X, Che Guevara, and Jesus, he transforms himself into a political antagonist.

Russell Brand sets out across America's vast heartland in homage to one of his literary heroes, Jack Kerouac, and his classic novel, On the Road. Travelling with his friend and co-host of his Radio 2 show The Russell Brand Show, he sets off on a coast-to-coast adventure that becomes a journey of self discovery.