In cases ripped from the headlines, police investigate serious and often deadly crimes, weighing the evidence and questioning the suspects until someone is taken into custody. The district attorney's office then builds a case to convict the perpetrator by proving the person guilty beyond a reasonable doubt. Working together, these expert teams navigate all sides of the complex criminal justice system to make New York a safer place.

Raymond "Red" Reddington, one of the FBI's most wanted fugitives, surrenders in person at FBI Headquarters in Washington, D.C. He claims that he and the FBI have the same interests: bringing down dangerous criminals and terrorists. In the last two decades, he's made a list of criminals and terrorists that matter the most but the FBI cannot find because it does not know they exist. Reddington calls this "The Blacklist". Reddington will co-operate, but insists that he will speak only to Elizabeth Keen, a rookie FBI profiler.

ER explores the inner workings of an urban teaching hospital and the critical issues faced by the dedicated physicians and staff of its overburdened emergency room.

After a one night stand with Alex, Isabel realizes that she is pregnant and they decide to get married. However, along with the marriage comes compromise of one's own cultural traditions.

Starting his new job as an instructor at a New England school for the deaf, James Leeds meets Sarah Norman, a young deaf woman who works at the school as a member of the custodial staff. In spite of Sarah's withdrawn emotional state, a romance slowly develops between the pair.

Ferro Olivetti, a billionaire playboy and businessman, promises to fulfill his dying father's final request: to live one month without his wealth.

Mother stands in for a runaway bride and marries the groom by proxy, then both set out to convince her daughter to reconsider. Later they mistake the missing bride and her companion for two escaped convicts and pursue them with a sex obsessed teenage boy in tow. All paths cross at a remote motel run by a jilted church deacon.