A look at a seemingly placid New England town that is actually wrought with illicit affairs, crime and tragedy, all told through the lens of Olive, whose wicked wit and harsh demeanor mask a warm but troubled heart and staunch moral center. The story spans 25 years and focuses on Olive's relationships with her husband, Henry, the good-hearted and kindly town pharmacist; their son, Christopher, who resents his mother's approach to parenting; and other members of their community.

Toru centers on the story of a baby boy, named Toru, born with a fatal lung condition. As he only has a few days to live Toru’s parents sign him up for a trial experiment that would simulate a full life in a matter of days. The film follows Toru’s dream-like life simulation as a boy named Todd growing up in a New England suburb, and concludes in futuristic Japan.