Dr. Gregory House, a drug-addicted, unconventional, misanthropic medical genius, leads a team of diagnosticians at the fictional Princeton–Plainsboro Teaching Hospital in New Jersey.

Dexter Morgan, a blood spatter pattern analyst for the Miami Metro Police also leads a secret life as a serial killer, hunting down criminals who have slipped through the cracks of justice.

Dr. Temperance Brennan and her colleagues at the Jeffersonian's Medico-Legal Lab assist Special Agent Seeley Booth with murder investigations when the remains are so badly decomposed, burned or destroyed that the standard identification methods are useless.

The show follows Crime Scene Investigators working for the Miami-Dade Police Department as they use physical evidence, similar to their Las Vegas counterparts, to solve grisly murders. The series mixes deduction, gritty subject matter, and character-driven drama in the same vein as the original series in the CSI franchise, except that the Miami CSIs are cops first, scientists second.

Adrian Monk was once a rising star with the San Francisco Police Department, legendary for using unconventional means to solve the department's most baffling cases. But after the tragic (and still unsolved) murder of his wife Trudy, he developed an extreme case of obsessive-compulsive disorder. Now working as a private consultant, Monk continues to investigate cases in the most unconventional ways.

ER explores the inner workings of an urban teaching hospital and the critical issues faced by the dedicated physicians and staff of its overburdened emergency room.

Hotshot plastic surgeons Dr. Sean McNamara and Dr. Christian Troy experience full-blown midlife crises as they confront career, family and romance problems.

Nearly 20 years ago, Owen Strand was the lone survivor of his Manhattan firehouse on 9/11. In the wake of the attack, Owen had the unenviable task of rebuilding his station. After a similar tragedy happens to a firehouse in Austin, Owen, along with his troubled firefighter son, T.K., takes his progressive philosophies of life and firefighting down to Texas, where he helps them start anew. On the surface, Owen is all about big-city style and swagger, but underneath he struggles with a secret he hides from the world - one that could very well end his life.

Blindsided by a new generation of blazing-fast racers, the legendary Lightning McQueen is suddenly pushed out of the sport he loves. To get back in the game, he will need the help of an eager young race technician with her own plan to win, inspiration from the late Fabulous Hudson Hornet, and a few unexpected turns.

Set in the aftermath of Jax Teller’s death, Ezekiel "EZ" Reyes is fresh out of prison and a prospect in the Mayans M.C. charter on the Cali/Mexi border. Now, EZ must carve out his new identity in a town where he was once the golden boy with the American Dream in his grasp.

Major Crimes explores how the American justice system approaches the art of the deals as law enforcement officers and prosecutors work together to score a conviction. Los Angeles Police Captain Sharon Raydor heads up a special squad within the LAPD that deals with high-profile or particularly sensitive crimes.

Jules Cobb is a mom in her forties facing the often humorous challenges, pitfalls and rewards of life's next chapter. Along for the journey is her son, her ex-husband, her husband/neighbor and her friends who together make up her dysfunctional, but supportive and caring extended family... even if they have a funny way of showing it sometimes.

Danny Ocean's team of criminals are back and composing a plan more personal than ever. When ruthless casino owner Willy Bank doublecrosses Reuben Tishkoff, causing a heart attack, Danny Ocean vows that he and his team will do anything to bring down Willy Bank along with everything he's got. Even if it means asking for help from an enemy.

A suburban neurotic man in his late 20s has convinced himself that he’s destined to be one of the best rappers of all time. Now he must convince his closest friends, because with their help, he might actually convince the world.

From the tony Beverly Hills to the seedy side of Hollywood, LAPD’s elite Robbery Homicide Division is on the case. Fusing classic ripped-from-the-headlines storytelling with the backdrop of LA, the series delves into the high profile crimes of the west coast.

When corruption charges strip him of his job, his family and his pride, former cop Mike Olshansky forges a new identity as a Philadelphia cab driver, patrolling the city as a roving vigilante who works with local police.

Serial monogamist Brian O'Hara hits his mid-30s and suddenly realizes he's the last bachelor standing in his circle of friends. Not averse to the happily ever after his friends have achieved, Brian wonders whether he'll ever find Mrs. Right. The fact that he's in love with his best friend's girlfriend doesn't help his chances.

A man who specializes in debunking paranormal occurrences checks into the fabled room 1408 in the Dolphin Hotel. Soon after settling in, he confronts genuine terror.

Ryden Malby has a master plan. Graduate college, get a great job, hang out with her best friend and find the perfect guy. But her plan spins hilariously out of control when she’s forced to move back home with her eccentric family.

Chang, a 16-year-old, Asian American, bets the high school basketball star that he can dunk by Homecoming. The bet leads 5' 8" Chang on a quest to learn to dunk—not only to impress his crush, Kristy, but to gain the respect of his high school peers too. But before he can rise up and truly throw one down, he'll have to reexamine everything he knows about himself, his friendships and his family.