The gang from Dorm Daze is back, but this time they're on a cruise ship on a tropical voyage through the high seas. The cruise makes an educational stop at the island of San Paradiso, where the students are supposed to explore an important archaeological site. Things go from normal to crazy as their visit coincides with every other college's spring break. The moment the boat docks, classes are over! For these Billingsley students, their Semester at Sea will be an adventure no one will ever forget.

When a foreign-exchange student and a hooker - both named Dominique - show up on a college campus, the unsuspecting student body is in for the education of a lifetime!