In 1974, Chilean-French director Alejandro Jodorowsky embarked on the quixotic project of adapting Frank Herbert's influential novel Dune (1969) for the big screen. After investing two years, and millions of dollars, the gigantic project ended in failure; but the artists Jodorowsky brought together to carry it out continued to work together, and ended up laying the foundations for modern science fiction cinema.

In this erstwhile comedy, Penelope (Isabelle Adjani) is already sufficiently unsettled by the fact that she is no longer a top model, and must cast around for another occupation. When her boyfriend leaves her, she becomes quite hysterical, conjuring up schemes for revenge, contemplating suicide, and so on. These dramatics eventually exasperate her best friend Sophie (Clementine Celarie) so much that she contemplates killing Penelope, her ex-boyfriend, or the two of them together, just to stop the whining.