Dr. Nathaniel Grant is a pioneering organ-transplant surgeon who takes risks that other doctors would not in order to save the lives of his patients. He works closely with his ex-wife, Kate Armstrong, an organ-donor coordinator with whom he has a volatile relationship. Grant's arrogance and willingness to perform risky procedures causes him to butt heads with the hospital administration. But his main focus is on his intense relationship with his job and his patients, often at the expense of his family.

Henry Poole abandons his fiancée and family business to spend what he believes are his remaining days alone. The discovery of a 'miracle' by a nosy neighbor ruptures his solitude and restores his faith in life.

Sully is a psychotic criminal who has just been released from prison. Now he has only one goal: revenge against police detective Elaine Reynolds, who he blames for the death of his wife's unborn child.

Truman, Weasel, and Doug videotape everything! From their Jackass-style pranks and death-defying stunts to their sleazy sexual conquests, they record it all with their camcorder! When a shy girl named April rebuffs Truman at a party, he makes a wager with Weasel and Doug that either convinces April to have sex with him or he pays them a hundred bucks each. Truman invites April to a desolate cabin for the weekend with Weasel behind the hidden camera to unknowingly capture the few, final agonizing hours of April's life!

A teen seductress pulls three other privileged Malibu kids into her devious scheme, and unforeseen consequences force the group to face their own fears and mortality.

In this dark comedy, a deaf housewife gets rid of her abusive husband and seeks the Highlife by becoming a hired assassin.

An Iraq war hero matches wits with an anti-war radical over the heart of a woman, forcing all three to confront their illusions of love, honor and country.