Convenience and video store clerks Dante and Randal are sharp-witted, potty-mouthed and bored out of their minds. So in between needling customers, the counter jockeys play hockey on the roof, visit a funeral home and deal with their love lives.

A gang of thugs devise a cruel hoax that goes horribly wrong as Melvin, a nerdy emaciated janitor at the local health club, is cast through a third story window into a vat of hazardous toxic waste.

A horrific explosion creates a dimensional portal between Tromaville and its dimensional mirror image, Amortville. While the Toxie is trapped in the mirror dimension, Tromaville comes under the control of his evil doppelganger, the Noxious Offender.