Four egocentric friends run a neighborhood Irish pub in Philadelphia and try to find their way through the adult world of work and relationships. Unfortunately, their warped views and precarious judgments often lead them to trouble, creating a myriad of uncomfortable situations that usually only get worse before they get better.

Dr. Jacob Hood is a brilliant biophysicist and special science advisor to the government who investigates scientific crises and oddities. His crusade is to protect the substance of science against those who would abuse and misuse scientific discoveries for their own gain.

It sounds like a budding writer's dream: a bestselling first novel, a luxurious house in Malibu, and a trophy wife... But it all unravels when writer's block and a failed marriage send Richard McMurray out into the streets.