George Bailey has spent his entire life giving to the people of Bedford Falls. All that prevents rich skinflint Mr. Potter from taking over the entire town is George's modest building and loan company. But on Christmas Eve the business's $8,000 is lost and George's troubles begin.

A married farmer falls under the spell of a slatternly woman from the city, who tries to convince him to drown his wife.

Three brothers stop off for a night in the town of Tombstone. The next morning they find one of their brothers dead and their cattle stolen. They decide to take revenge on the culprits.

An unemployed drifter, Eric Stanton wanders into a small California town and begins hanging around the local diner. While Eric falls for the lovely waitress Stella, he also begins romancing a quiet and well-to-do woman named June Mills. Since Stella isn't interested in Eric unless he has money, the lovelorn guy comes up with a scheme to win her over, and it involves June. Before long, murder works its way into this passionate love triangle.

As a parting shot, fired reporter Ann Mitchell prints a fake letter from unemployed "John Doe," who threatens suicide in protest of social ills. The paper is forced to rehire Ann and hires John Willoughby to impersonate "Doe." Ann and her bosses cynically milk the story for all it's worth, until the made-up "John Doe" philosophy starts a whole political movement.

When transplanted Texan Bob Seton arrives in Lawrence, Kansas he finds much to like about the place, especially Mary McCloud, daughter of the local banker. Politics is in the air however. It's just prior to the civil war and there is already a sharp division in the Territory as to whether it will remain slave-free. When he gets the opportunity to run for marshal, Seton finds himself running against the respected local schoolteacher, William Cantrell. Not is what it seems however. While acting as the upstanding citizen in public, Cantrell is dangerously ambitious and is prepared to do anything to make his mark, and his fortune, on the Territory. When he loses the race for marshal, he forms a group of raiders who run guns into the territory and rob and terrorize settlers throughout the territory. Eventually donning Confederate uniforms, it is left to Seton and the good citizens of Lawrence to face Cantrell and his raiders in one final clash.

Madcap couple George and Marion Kerby are killed in an automobile accident. They return as ghosts to try and liven up the regimented lifestyle of their friend and bank president, Cosmo Topper. When Topper starts to live it up, it strains relations with his stuffy wife.

The Florida Keys in 1840, where the implacable hurricanes of the Caribbean scream, where the salvagers of Key West, like the intrepid and beautiful Loxi Claiborne and her crew, reap, aboard frail schooners, the harvest of the wild wind, facing the shark teeth of the reefs to rescue the sailors and the cargo from the shipwrecks caused by the scavengers of the sea.

In Brooklyn circa 1900, the Nolans manage to enjoy life on pennies despite great poverty and Papa's alcoholism. We come to know these people well through big and little troubles: Aunt Sissy's scandalous succession of "husbands"; the removal of the one tree visible from their tenement; and young Francie's desire to transfer to a better school...if irresponsible Papa can get his act together.

A New York inventor, Tom Jeffers, needs cash to develop his big idea, so his adoring wife, Gerry, decides to raise it by divorcing him and marrying an eccentric Florida millionaire, J. D. Hackensacker III.

After a newlywed's husband apparently dies in a plane crash, she discovers that her rival for his affections is pregnant with his child.

Ordinary man-in-the-street Arthur Ferguson Jones leads a very straightforward life. He's never late for work and nothing interesting ever happens to him. One day everything changes: he oversleeps and is fired as an example, he's then mistaken for evil criminal killer Mannion and is arrested. The resemblance is so striking that the police give him a special pass to avoid a similar mistake. The real Mannion sees the opportunity to steal the pass and move around freely and chaos results.

Despite her mother's objections, the naive young daughter of a show boat captain is thrust into the limelight as the company's new leading lady.

When composer George Harvey Bone wakes with no memory of the previous night and a bloody knife in his pocket, he worries that he has committed a crime. On the advice of Dr. Middleton, Bone agrees to relax, going to a music performance by singer Netta Longdon. Riveted by Netta, Bone agrees to write songs for her rather than his own concerto. However, Bone soon grows jealous of Netta and worries about controlling himself during his spells.

Teenager Susan Turner, with a severe crush on playboy artist Richard Nugent, sneaks into his apartment to model for him and is found there by her sister Judge Margaret Turner. Threatened with jail, Nugent agrees to date Susan until the crush abates.

When Willie leaves home to join the war effort he is all ready to become a hero, but he is only frustrated when his posting ends up to be in his home town, and he is recruited into training, keeping him from the action. However, when he finds himself accidently behind enemy lines he unexpectedly becomes a hero after all.

Frank Johnson, a sole witness to a gangland murder, goes into hiding and is trailed by Police Inspector Ferris, on the theory that Frank is trying to escape from possible retaliation. Frank's wife, Eleanor, suspects he is actually running away from their unsuccessful marriage. Aided by a newspaperman, Danny Leggett, Eleanor sets out to locate her husband. The killer is also looking for him, and keeps close tabs on Eleanor.

Reporters Clark Kent and Lois Lane arrive in the small town of Silsby to witness the drilling of the world's deepest oil well. The drill, however, has penetrated the underground home of a race of small, furry people who then come to the surface at night to look around. The fact that they glow in the dark scares the townfolk, who form a mob, led by the vicious Luke Benson, intent on killing the strange people. Only Superman has a chance to prevent this tragedy.

Brandon, a surveyor, dreams of building a railway to the west. He sets off with his son, Davy, to survey a route. They discover a new pass which will shave 200 miles off the expected distance, but they are set upon by a party of Cheyenne. One of them, a white renegade with only two fingers on his right hand, kills Brandon and scalps him. Davy is all alone now.

A millionaire automaker retires upon the advice of his doctor, but becomes so bored he buys half interest in a gas station and works it on the sly.