Crawldaddy and her two kids are travelling across the country on the search for victims. The dysfunctional family has the disturbing habit of skinning people alive before killing them. When their van breaks down, they are put up by a friendly couple.

Jeff works the night shift, then comes home to his domineering mother, who has the grisly habit of slaughtering neighborhood children to satisfy her insatiable bloodlust. Jeff is reluctant to reveal his true identity until he meets Nina, a young woman with a strange attraction for the introvert. But Jeff’s not the only one with eyes for Nina… mother has other plans for her!