The trials and tribulations of finding love and companionship — the second time around. Newly divorced Alex, who is missing his kids and trying to keep himself together. Alex's co-worker Helen thinks she has it together, but she drinks too much in order to cope with her fiance's untimely death. It's no surprise then when these two overworked public relations executives share an ill-fated night of passion and are forced to cope with the awkward aftermath.

One bar. One night. Ten single people. Welcome to Mix, a high-end bar in Manhattan's trendy meatpacking district.  These are the exploits of singles, five guys and five girls, in search of love - all over the course of one night.

A drama following multiple characters as they weave through their daily lives searching for happiness. However, happiness to each of them is defined differently. The film moves through its various stories without attempting to make character intersections any more meaningful than the random nature of life itself; the effect is a sprawling mosaic of New York City and its everyday people, living everyday lives.