William Masters and Virginia Johnson are real-life pioneers of the science of human sexuality. Their research touched off the sexual revolution and took them from a midwestern teaching hospital to the cover of Time magazine and multiple appearances on Johnny Carson's couch. He is a brilliant scientist out of touch with his own feelings, and she is a single working mother ahead of her time. The series chronicles their unusual lives, romance, and unlikely pop culture trajectory.

Less tells the story of Finn Norman, a renegade artist who has severed all ties with his past to make his home on the streets. Living off what others throw away, Finn’s quest for a life free from attachment is threatened by his growing connections with a painfully shy cafe girl and a grizzled street performer.