Samantha Stephens is a seemingly normal suburban housewife who also happens to be a genuine witch, with all the requisite magical powers. Her husband Darrin insists that Samantha keep her witchcraft under wraps, but situations invariably require her to indulge her powers while keeping her bothersome mother Endora at bay.

Mother Carey, a Bostonian widow, and her three children move to Maine. Postmaster Osh Popham helps them move into a run-down old house and fixes it up for them. It's not entirely uninhabited, though; the owner, Mr. Hamilton, is a mysterious character away in Europe, but Osh assures them he won't mind their living there, since he won't be coming home for a long time yet. The children and a cousin who comes to live with them have various adventures before an unexpected visitor shows up

Elderly cowboy Will Lane arranges marriage of wild son of dead friend to tame him.

Cory Weissman is a college basketball player who suffers a devastating stroke. He perseveres to find new meaning in his life both on, and more importantly, off the court.

Young doctors mix romance with their careers in a big-city hospital.