After escaping from jail, outlaw Wes McQueen is convinced by his old partner in crime to do one last heist.

The nefarious Dr. Fu Manchu searches for the keys to the tomb of Genghis Khan, in order to fulfill a prophecy that will enable him to conquer the world. His nemesi, Dr. Nayland Smith and his associates fight to keep the evil doctor from getting his hands on the keys. In 1943 the serial was edited together into a feature movie also called Drums of Fu Manchu.

Dorn is after the rancher's land and is trying to stop Banker Brady from helping them. When his man Hammond kills Brady, there is a run on the bank. When Rocky volunteers to ride to the next town for money, he is ambushed by Dorn's men, loses his memory, and is jailed for supposedly stealing the money.

John Martin is a government agent working under cover. Leading citizen Morgan calls in gunman Galt who blows Martin's cover.

The Cattlemen's Association has called in the Mesquiteers to find cattle rustlers. They get Tex Riley to pose as Stony so Stony can arrive posing as a wanted outlaw. This gets Stony into the gang of rustlers and he alerts Tucson and Lullaby as to the next raid. But Hartley is on hand and unknown to anyone is the rustler's boss and he joins the posse with a plan that will do away with the Mesquiteers.

Homesteaders are moving into the valley settled many years ago by rancher Craig Dolan. He wants to keep them out by legal means but his nephew Bart brings in outlaws to drive them out. The Lone Ranger is on hand to help the homesteaders battle Bart's men as he overcomes traps, ambushes, burning buildings and other obstacles in his attempt to bring peace to the valley.

A villainous banker and his hired saboteurs attempt to thwart construction of Sweetwater Dam.

A city girl on a bus tour of the West encounters a handsome rodeo cowboy who helps her forget her city suitors.

Stanton breaks Billy and his two friends Fuzzy and Jeff out of jail. He wants them free so three of his men can impersonate them for the robberies and murders he has planned.

When Billy Carson's uncle is lynched as a supposed rustler, Billy arrives looking for the murderers. He finds that Steve Kirby holds a forged note on his Uncle's ranch. When Kirby sees that Billy means trouble for him, he has him framed for murder. Then just as he is inciting the mob to lynch him, Billy's new friend Doc Jones is trying to break him out of jail.

The mysterious Don Del Oro ("Lord of Gold"), an idol of the Yaqui Indians, plans to take over the gold and become Emperor. Francisco was put in charge of a legion to combat the Yaqui tribe and protect the land, but when attacked Zorro came to his rescue. Francisco's partner recognized Zorro as the hidalgo Don Diego Vega, then ask him to take over the fighting legion as his alter-ego Zorro.

Dave Crockett (Bill Elliott) comes to the aid of ranchers living on the Yucca Strip, who want their area made part of the United States. A greedy land baron, however, wants the property as his own.

Tom Cameron is searching for the outlaws who ambushed a wagon train, murdered his parents and stole the deed to their land. Though he was only a child at the time, he vividly remembers the scar on the ringleader's face -- and Tom will stop at nothing until he brings him to justice … and exacts vengeance.

Columbia's 11th serial and the first western serial that James W. Horne solo-directed.

Billy and his pals, on the run from the law again, travel to Sage Valley where Billy is made Sheriff. The local outlaw gang is run by Kansas Ed who closely resembles Billy. Ed captures Billy and changing clothes with him, now plans to run the town as Sheriff.

To get the three needed business men to visit the Stevens mine, Roy stages a ride with the Vacaros and has them as honored guests. Seeing a chance to make a lot of money, gangster Harmon joins the ride and then has his men kidnap the three. Having filmed a fake holdup earlier, he uses the film to convince the Sheriff that Roy and the boys were the Kidnapers.

Harkness controls Boulder Pass and his men are overcharging the ranches for its usage. When Tom Cameron steps in to rob the tollgate keepers and return the money to the ranchers, he gets caught.

When three Texas Rangers try to investigate kidnapped Mexicans being used as forced labor in the mines of Silver Bullet, they are framed for murder by the town's corrupt sheriff.

Two deputies go undercover to save a scientist from his evil kidnappers.

A drought is about to end the cattle business. The owner of a canning factory wants to buy all the remaining cattle cheap. He plans to ruin the cattlemen's plans to ship water by train and to seed the clouds for rain. Roy is sent by a packing house to investigate.