Warren Quimby manages a drugstore while trying to keep his volatile wife, Claire, happy. However, when Claire leaves him for a liquor store salesman, Warren can no longer bear it. He decides to assume a new identity in order to murder his wife's lover without leaving a trace. Along the way, his plans are complicated by an attractive neighbor, as well as a shocking discovery that opens up a new world of doubts and accusations.

A mechanical brain is programmed to sabotage the government's secret lab while working on the first space station.